Voltage-gatedsodiumchannels相关论文
Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Spec
Voltage-gated sodium channels (Navs) play an important role in human pain sensation.However,the expression and role of N......
Alm: To analyze both the expression and distribution of the voltage-gated sodium channels (VGSCs) subtypes-Nav1.1, Nav1.......
Sensitization of sodium channels contributes to colonic visceral hypersensitivity in diabetic rats a
Background:Intestinal dysfunction is a common chronic complication of diabetes mellitus,the underlying mechanisms of col......
The Effect of Pulse Radiofrequency on Pain Behavior and Function of Voltage-gated Sodium Channels in
Objective: To investigate the effect of pulse radiofrequency(PRF)on pain behavior,and current densities,kinetic properti......
Interaction between beta subunits and extracellular mat rix modulating sodium channels-involved mirr
Voltage-gated sodium(Nav)channels play key roles in induction,transmission,transduction of pathological pain.Nav channel......
Anticonvulsant effect of BmK IT2, a sodium channel-specific neurotoxin, in experimental epilepsy mod
In the present study,the anticonvulsant effect of BmK IT2,a sodium channel-specific polypeptide purified from the venom ......
Low Mg2+ treatment increases the sensitivity of voltage-gated sodium channels to the Ca2+/calmodulin
The purpose of this study was to investigate the effect of Ca2+/calmodulin (CaM) on voltage-gated sodium channels (VGSCs......
Molecular basis of the tarantula toxin Jingzhaotoxin-Ⅲ(β-TRTX-Cj 1a) interacting with Voltage Sensor
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Inhibitory effects of bufalin,an analgesic ingredient from toad venom on voltage-gated sodium channe
Bufonis Venenum(toad venom)is always used for analgesia in China from ancient to modern times.Bufalin,a non-peptide toxi......
Interaction between beta subunits and extracellular matrix mo dulating sodium channels-involved mirr
Voltage-gated sodium (Nav) channels play key roles in induction, transmission,transduction of pathological pain.Nay chan......
Dynamic expression of VGSCs subtypesNav1.1, Nav1.2,Nav1.3 and Nav1.6 triggered by BmK I in rat hippo
BmK I (an-like toxin purified from the venom of Eastem Asian scorpion Buthus martensi Karsch) has been identified to a s......
Inhibition of cystathionine β-synthetase desensitizes sodium channel activities of dorsal root gangl
Background: The pathogenesis of pain in lumber disc herniation (LDH) remains poorly understood.We have previously report......
CalciumCalmodulin-dependent Protein Kinase Ⅱ Inhibition Induces Hyperexcitability by Abnormal Intera
Abnormal calcium/calmodulin (CaM)-dependent kinase Ⅱ (CaMKⅡ) changes have been shown to be involved in many epilep......
The mechanism of Na(+)K(+) selectivity in Mammalian voltage-gated sodium channels based on molecular
Background: Voltage-gated sodium (Nav) channels and their Na+/K+ selectivity are of great importance in the mammalia......
Sodium channel beta subunits and extracellular matrix modulating mirror image pain induced by scorpi
Voltage-gated sodium (Nay) channels play key roles in induction, transmission,transduction of pathological pain.Nay ......
电压门控钠离子通道兴奋性细胞中高表达,并且在总电位的去极化及神经递质的分泌和释放过程中发挥着重要的作用。最新研究表明,电压门......
Functional Expression of Voltage-Gated Sodium Channels Navl.5 in Human Breast Caner Cell Line MDA-MB
Voltage-gated sodium channels (VGSCs) are known to be involved in the initiation and progression of many malignancies,an......